What Are The Target Organ Of Vinyl Chloride

The liver appears to be the most sensitive target organ of vinyl chloride.

What are the target organ of vinyl chloride.

Vinyl chloride monomer page 1 of 8 sds no. The cns is the primary target of vinyl chloride acute toxicity. When confined under high pressure in special containers vinyl chloride exists in a liquefied state. Box 24440 doha state of qatar.

The following is a target organ categorization of effects which may occur from exposure to hazardous chemicals including examples of signs and symptoms and. The primary route of vinyl chloride exposure is inhalation. Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body. Target organ effect the target organs and potential effects of vinyl chloride exposure include.

Vinyl chloride is an organochloride with the formula h 2 c chcl that is also called vinyl chloride monomer vcm or chloroethene this colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride pvc. Additional research has now demonstrated the carcinogenicity of vc to other organs and at lower concentrations. The target organs for vc now clearly in. Table 1 target organs and potential effects of vinyl chloride exposure target organ effect.

At room temperature vinyl chloride is a colorless highly flammable potentially explosive gas. It has a faint sweet odor. About 13 billion kilograms are produced annually. In 1974 vinyl chloride vc was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals.

Makarov et al 1984. There may be a latent period of hours to days between exposure and symptom onset. Target organs liver central nervous system blood respiratory system lymphatic system cancer site liver cancer. Vinyl chloride is thought to depress the cns via a solvent effect on lipids and protein components of neural membranes that interrupt signal transmission.

Qatar vinyl company ltd. Occupational exposure to vinyl chloride has been associated with reduced sexual function in both sexes and gynecological effects in women makarov 1984. Noncancerous hepatotoxicity and carcinogenicity of vinyl chloride are discussed in greater detail below. Accidental ingestion may be possible when eating or smoking with contaminated hands.

Toxins do not affect all organs in the body to the same extent due to their different cell structures. The reader is referred to section 3 2 discussion of health effects by route of exposure for additional information on other effects. For the oral route of exposure the primary target organ of vinyl chloride toxicity in animals is the liver. 12 10 2017 01 identification of the substance preparation and the company undertaking product name vinyl chloride monomer sds no.

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